WHO’s Strategic Advisory Group of Consultants on Immunization (SAGE) has issued its coverage suggestions for the rollout of the primary COVID-19 vaccine authorised for emergency use, the Pfizer-BioNTech COVID-19 vaccine.
In line with SAGE, the Pfizer-BioNTech COVID-19 mRNA vaccine is protected and efficient. Nonetheless, there are particular populations for whom vaccination is just not really helpful, both because of contraindications, lack of provide, or restricted information. These populations at the moment embrace folks with a historical past of extreme allergy symptoms, most pregnant ladies, worldwide travellers who aren’t a part of a prioritized group, and kids underneath 16.
he precedence is to start out vaccinating well being staff at excessive threat of publicity, adopted by older adults, earlier than immunizing the remainder of the inhabitants.
Individuals with allergy symptoms
Individuals with a historical past of extreme allergic response to any element of the vaccine shouldn’t take it.
Pregnant and breastfeeding ladies
Pregnant ladies are at greater threat of extreme COVID-19 than non-pregnant ladies, and COVID-19 has been related to an elevated threat of pre-term delivery.
Nonetheless because of inadequate information, WHO doesn’t advocate the vaccination of pregnant ladies right now.
In case a pregnant girl has an unavoidable threat excessive of publicity (e.g. a well being employee), vaccination could also be thought of in dialogue with their healthcare supplier.
It is strongly recommended to keep away from being pregnant for two to three months post-vaccination.
If a breastfeeding girl is a part of a bunch (e.g. well being staff) really helpful for vaccination, vaccination may be supplied. WHO doesn’t advocate discontinuing breastfeeding after vaccination.
The vaccine has solely been examined in kids above 16 years of age.
Due to this fact, right now, WHO doesn’t advocate vaccination of kids beneath 16 years of age, even when they belong to a high-risk group.
Individuals with recognized medical circumstances
The vaccine has been discovered to be protected and efficient in folks with varied circumstances which might be related to elevated threat of extreme illness.
This consists of hypertension, diabetes, bronchial asthma, pulmonary, liver or kidney illness, in addition to continual infections which might be secure and managed.
Additional research are required for the impacts on immune-compromised individuals. The interim suggestion is that immune-compromised individuals who’re a part of a bunch really helpful for vaccination could also be vaccinated, although when attainable, not earlier than receiving info and counselling.
Individuals dwelling with HIV are at greater threat of extreme COVID-19 illness. Restricted security information exists on HIV-infected individuals with nicely managed illness from the medical trials. Identified HIV-positive vaccine recipients needs to be knowledgeable, and when attainable, counselled in relation to the out there information.
Individuals who have or had COVID-19 already
Vaccination may be supplied to individuals who have had COVID-19 previously.
However given the restricted vaccine provide, people could want to defer their very own COVID-19 vaccination for as much as 6 months from the time of SARS-CoV-2 an infection. As extra information turns into out there on length of immunity after an infection, this time interval could also be adjusted.
Testing for prior an infection is just not really helpful for the aim of vaccine decision-making.
At current, WHO doesn’t assist the introduction of necessities for proof of vaccination towards COVID-19 for worldwide vacationers as a situation for exiting or coming into a rustic or for travelling internationally. See WHO’s interim steerage on worldwide journey throughout the pandemic.
A protecting impact begins to develop 12 days after the primary dose, however full safety requires two doses which WHO recommends be administered with a 21 to 28-day interval. Further analysis is required to know longer-term potential safety after a single dose.
Vaccines is not going to finish COVID-19 alone
Protected and efficient vaccines will likely be a gamechanger: however for the foreseeable future we should proceed to put on masks, bodily distance, keep away from crowds and apply different well being measures. Being vaccinated does not imply that we will throw warning to the wind and put ourselves and others in danger, notably as a result of it’s nonetheless not clear the diploma to which the vaccines can shield not solely towards illness but in addition towards an infection and transmission.
What about different vaccines being developed to combat COVID-19
WHO doesn’t often make vaccine particular suggestions, issuing as a substitute one suggestion that covers all vaccines for a given illness, until the proof suggests a distinct strategy is required.
As a result of giant number of COVID-19 vaccines primarily based on very totally different platform applied sciences, WHO is vaccines are they’re being authorised by extremely competent nationwide regulatory authorities and which might be out there in adequate provide to deal with the wants of many nations.
WHO has no most popular product, and the number of merchandise, together with their particular attributes and dealing with necessities, permit for nations to search out the merchandise which might be best suited for his or her circumstances.
WHO’s SAGE is predicted to evaluate different vaccines within the coming months.
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